The
sarcolemma is the cell membrane of a muscle cell (skeletal, cardiac, and smooth muscle It consists of a true cell membrane, called
Kaynak: SarcolemmaA T-tubule (or transverse tubule) is a deep invagination of the
sarcolemma , which is the plasma membrane , only found in skeletal and
Kaynak: T-tubuleExternal lamina is a structure similar to basal lamina that surrounds the
sarcolemma of muscle cells. It is secreted by myocytes and
Kaynak: External laminathe synapse and binds nicotinic acetylcholine receptor s (nAChRs) on the plasma membrane of the muscle fiber, also known as the
sarcolemma .
Kaynak: Neuromuscular junctionDystrophin is a protein located between the
sarcolemma and the outermost layer of myofilament s in the muscle fiber (myofiber ).
Kaynak: DystrophinMyosatellite cells are located between the basal lamina and
sarcolemma of muscle fibers, and can lie in grooves either parallel or
Kaynak: Myosatellite cellThey physically couple force-generating sarcomeres with the
sarcolemma in striated muscle cells and are thus considered one of several "
Kaynak: Costamereidentified by their position within the cell as being either
sarcolemma l ("sarcK ATP"), mitochondrial ("mitoK ATP"), or nuclear ("nucK ATP").
Kaynak: ATP-sensitive potassium channelconnecting the muscle fibre cytoskeleton to the extracellular matrix , preventing damage to the muscle fibre
sarcolemma through shearing forces.
Kaynak: SarcoglycanIt has a Golgi apparatus , near the nucleus , mitochondria just on the inside of the cytoplasmic membrane or
sarcolemma , as well as a
Kaynak: SarcoplasmOriginates in the myofibrae, affecting the
sarcolemma , or skeletal muscle cell membrane. Symptoms of muscle weakness and hypotonia
Kaynak: Congenital myopathySubsequently, alpha syntrophin was shown to be the predominant isoform in skeletal muscle where it is localized on the
sarcolemma and
Kaynak: Syntrophineventually are attached to adherens junctions (also called focal adhesions) in the cell membrane of the smooth muscle cell, called the
sarcolemma .
Kaynak: Smooth muscle tissueDystrophin links actin (cytoskeleton) and dystroglycans of the muscle cell plasma membrane, known as the
sarcolemma (extracellular).
Kaynak: Muscular dystrophyan integral membrane protein in the membrane (the
sarcolemma ) of the muscle fiber However, the acetylcholine does not remain bound;
Kaynak: Action potentialIn the human fetus during muscle differentiation , utrophin is found at the
sarcolemma . It disappears when the fetus begins to express
Kaynak: Utrophinmuscular dystrophies, glycosyltransferases in neurons and muscle cells, the neuromuscular junction and molecular architecture of the
sarcolemma.
Kaynak: Derek Blake